Positive and Negative Emotions and Coping as Mediators of Mother-Child Attachment and Peer Relationships

This study examined whether emotions and coping explain (mediate) the association between mother-child attachment and peer relationships. Attachment, positive and negative emotion experience, coping, and peer relationships were examined in 106 fourth-grade through sixth-grade girls attending a 6-day residential camp. Attachment, experience of positive and negative emotions, and coping were measured prior to camp with questionnaires completed by girls and their mothers. Girls reported the quality of their best friendship at camp, and camp counselors rated girls’ peer competence. Girls who perceived a more secure attachment to mother reported experiencing more positive and less negative emotions, were reported by mothers to use more social-support coping, reported more positive qualities in camp best friendships, and were rated by counselors as having enhanced peer relationships at camp. Further, the experience of positive emotions, problem-solving coping, and social-support coping mediated the links between attachment and peer relationships

Apego y emociones en la niñez media y adolescencia

The purpose of this review is to summarize and evaluate the current state of the literature with regards to attachment and its relationship to emotion in middle childhood and adolescence. This is a relatively new topic of interest and one which is well grounded in theory. The attachment relationship between parents and children is a key mechanism by which children and adolescents learn emotion skills, including emotion understanding, coping strategies, and how to manage different affective experiences. The review is organized by emotion domain, including emotion understanding, affective experiences, physiological indicators of arousal and emotion, and processes for the regulation of emotion. We included studies which presented data for children and adolescents ages 6-18, and included measures of emotion and parent-child attachment. Although some areas have been investigated more than others, we found that secure attachment was related to more adaptive functioning in each of the emotion domains. Finally, we review future directions to be explored and address gaps in the current literature.El propósito de este análisis es resumir y evaluar es estado actual de la literatura con respecto al apego y su relación con emociones en la niñez media y adolescencia. Este es un tema de interés relativamente nuevo y con buenos conocimientos teóricos. La relación de apego entre los padres y los hijos es el mecanismo clave a través del cual los hijos y adolescentes aprenden destrezas emocionales, incluido entendimiento emocional, estrategias de afrontamiento y cómo manejar diferentes experiencias afectivas. El análisis es organizado según las competencias emocionales, incluido entendimiento emocional, experiencias afectivas, indicadores fisiológicos de excitación y emociones, y procesos para la regulación de emociones. Hemos incluido estudios que presentan datos para niños y adolescentes de entre 6 y 18 años, y también medidas de emociones y apego padres-hijos. Aunque algunos campos fueron investigados mejor que otros, nosotros hemos comprobado que el apego seguro está relacionado con el funcionamiento más adaptado en cada uno de dominios emocionales. Finalmente, analizamos las direcciones futuras que están por explorar y abordamos los huecos en la literatura presente

Dynamics of attachment and emotion regulation in daily life : uni- and bidirectional associations

Attachment theory proposes that the activation of the attachment system enacts emotion regulation (ER) to maintain security or cope with insecurity. However, the effects of ER on attachment states and their bidirectional influences remain poorly understood. In this ecological momentary assessment study, we examined the dynamics between attachment and ER. We hypothesised that attachment states and ER influence each other through time. Specifically, we hypothesised bidirectional short-term cycles between state attachment security and reappraisal, state attachment anxiety and rumination, and state attachment avoidance and suppression. We also tested how trait attachment is related to state attachment and ER. One hundred twenty-two participants (M-age = 26.4) completed the Experiences in Close Relationship-Revised and reported state attachment and ER seven times daily for seven days. The results were only partly consistent with our cycle hypotheses yet revealed a cycle between low state attachment security and rumination that was attenuated by reappraisal. Moreover, rumination and suppression predicted increased insecure states, and reappraisal predicted increased secure and insecure states. Finally, trait attachment showed associations with state attachment and ER. Our study suggests regulatory dynamics between attachment and ER and opens important questions about their functional relationship in maintaining attachment-related behavioural patterns and emotional well-being.Peer reviewe

Measurement invariance across mother/child and father/child attachment relationships

We examine the factorial structure of the Security Scale Questionnaire (SSQ), exploring measurement invariance across mother-father-child attachment relationships, child sex, and country. We used the new 21-item SSQ version that integrates both safe haven and secure base behaviors in a two factors structure. Participants were 457 children (224 girls and 233 boys), ranging from 9 to 14 years old (M = 10.84, SD = 1.02) from Portuguese and USA samples. We confirmed the SSQ's two-factor structure, although four items were unrelated to the latent structure and excluded from the final model. Results showed that SSQ can be used to study both mother/child and father/child attachment relationships. Multi-group analyses suggested measurement invariance between boys and girls and between Portuguese and USA samples. Our findings suggest that the SSQ can be considered a valid and cost-effective tool to measure perceived attachment security in middle childhood for both mother/child and father/child relationships.info:eu-repo/semantics/publishedVersio

Geminin-Deficient Neural Stem Cells Exhibit Normal Cell Division and Normal Neurogenesis

Neural stem cells (NSCs) are the progenitors of neurons and glial cells during both embryonic development and adult life. The unstable regulatory protein Geminin (Gmnn) is thought to maintain neural stem cells in an undifferentiated state while they proliferate. Geminin inhibits neuronal differentiation in cultured cells by antagonizing interactions between the chromatin remodeling protein Brg1 and the neural-specific transcription factors Neurogenin and NeuroD. Geminin is widely expressed in the CNS during throughout embryonic development, and Geminin expression is down-regulated when neuronal precursor cells undergo terminal differentiation. Over-expression of Geminin in gastrula-stage Xenopus embryos can expand the size of the neural plate. The role of Geminin in regulating vertebrate neurogenesis in vivo has not been rigorously examined. To address this question, we created a strain of Nestin-Cre/Gmnnfl/fl mice in which the Geminin gene was specifically deleted from NSCs. Interestingly, we found no major defects in the development or function of the central nervous system. Neural-specific GmnnΔ/Δ mice are viable and fertile and display no obvious neurological or neuroanatomical abnormalities. They have normal numbers of BrdU+ NSCs in the subgranular zone of the dentate gyrus, and GmnnΔ/Δ NSCs give rise to normal numbers of mature neurons in pulse-chase experiments. GmnnΔ/Δ neurosphere cells differentiate normally into both neurons and glial cells when grown in growth factor-deficient medium. Both the growth rate and the cell cycle distribution of cultured GmnnΔ/Δ neurosphere cells are indistinguishable from controls. We conclude that Geminin is largely dispensable for most of embryonic and adult mammalian neurogenesis

Geminin Is Required for Zygotic Gene Expression at the Xenopus Mid-Blastula Transition

In many organisms early development is under control of the maternal genome and zygotic gene expression is delayed until the mid-blastula transition (MBT). As zygotic transcription initiates, cell cycle checkpoints become activated and the tempo of cell division slows. The mechanisms that activate zygotic transcription at the MBT are incompletely understood, but they are of interest because they may resemble mechanisms that cause stem cells to stop dividing and terminally differentiate. The unstable regulatory protein Geminin is thought to coordinate cell division with cell differentiation. Geminin is a bi-functional protein. It prevents a second round of DNA replication during S and G2 phase by binding and inhibiting the essential replication factor Cdt1. Geminin also binds and inhibits a number of transcription factors and chromatin remodeling proteins and is thought to keep dividing cells in an undifferentiated state. We previously found that the cells of Geminin-deficient Xenopus embryos arrest in G2 phase just after the MBT then disintegrate at the onset of gastrulation. Here we report that they also fail to express most zygotic genes. The gene expression defect is cell-autonomous and is reproduced by over-expressing Cdt1 or by incubating the embryos in hydroxyurea. Geminin deficient and hydroxyurea-treated blastomeres accumulate DNA damage in the form of double stranded breaks. Bypassing the Chk1 pathway overcomes the cell cycle arrest caused by Geminin depletion but does not restore zygotic gene expression. In fact, bypassing the Chk1 pathway by itself induces double stranded breaks and abolishes zygotic transcription. We did not find evidence that Geminin has a replication-independent effect on transcription. We conclude that Geminin is required to maintain genome integrity during the rapid cleavage divisions, and that DNA damage disrupts zygotic gene transcription at the MBT, probably through activation of DNA damage checkpoint pathways

Patient engagement in designing, conducting, and disseminating clinical pain research : IMMPACT recommended considerations

The consensus recommendations are based on the views of IMMPACT meeting participants and do not necessarily represent the views of the organizations with which the authors are affiliated. The following individuals made important contributions to the IMMPACT meeting but were not able to participate in the preparation of this article: David Atkins, MD (Department of Veterans Affairs), Rebecca Baker, PhD (National Institutes of Health), Allan Basbaum, PhD (University of California San Francisco), Robyn Bent, RN, MS (Food and Drug Administration), Nathalie Bere, MPH (European Medicines Agency), Alysha Croker, PhD (Health Canada), Stephen Bruehl, PhD (Vanderbilt University), Michael Cobas Meyer, MD, MBS (Eli Lilly), Scott Evans, PhD (George Washington University), Gail Graham (University of Maryland), Jennifer Haythornthwaite, PhD (Johns Hopkins University), Sharon Hertz, MD (Hertz and Fields Consulting), Jonathan Jackson, PhD (Harvard Medical School), Mark Jensen, PhD (University of Washington), Francis Keefe, PhD (Duke University), Karim Khan, MD, PhD, MBA (Canadian Institutes of Health Research), Lynn Laidlaw (University of Aberdeen), Steven Lane (Patient-Centered Outcomes Research Institute), Karen Morales, BS (University of Maryland), David Leventhal, MBA (Pfizer), Jeremy Taylor, OBE (National Institute for Health Research), and Lena Sun, MD (Columbia University). The manuscript has not been submitted, presented, or published elsewhere. Parts of the manuscript have been presented in a topical workshop at IASP World Congress on Pain in Toronto, in 2022.Peer reviewedPublisher PD

High school drinking mediates the relationship between parental monitoring and college drinking: A longitudinal analysis

<p>Abstract</p> <p>Background</p> <p>College drinking is a significant public health problem. Although parental monitoring and supervision reduces the risk for alcohol consumption among younger adolescents, few studies have investigated the impact of earlier parental monitoring on later college drinking. This study examined whether parental monitoring indirectly exerts a protective effect on college drinking by reducing high school alcohol consumption.</p> <p>Methods</p> <p>A longitudinal cohort of 1,253 male and female students, ages 17 to 19, attending a large, public, mid-Atlantic university was studied at two time points. First, data on high school parental monitoring and alcohol consumption were gathered via questionnaire during the summer prior to college entry. Second, during the first year of college, past-year alcohol consumption was measured via a personal interview. Multiple regression models tested the relationship between parental monitoring and past year alcohol use (i.e., number of drinks per drinking day).</p> <p>Results</p> <p>Holding constant demographics, SAT score, and religiosity, parental monitoring had a significant protective effect on both high school and college drinking level. However, the association between parental monitoring and college drinking level became non-significant once high school drinking level was held constant.</p> <p>Conclusion</p> <p>While parental monitoring did not directly influence college alcohol consumption, evidence for mediation was observed, whereby parental monitoring had an indirect influence on college drinking through reductions in high school drinking. Initiatives that promote effective parenting might be an important strategy to curb high-risk drinking among older adolescents. More research is needed to understand the nature and degree of parent-child communication that is necessary to extend the protective influence of parents into the college years.</p